Leftover Pizza Grilled Cheese

Featured in: Easy Everyday Warmth

This dish transforms cold pizza slices by folding them around juicy shredded chicken and optional extra cheese. The assembly is quickly toasted in butter until golden brown and melty. It combines crispy crust and gooey filling for a comforting, easy-to-make meal using leftover ingredients. Perfect for a snack or light main, it requires minimal preparation and integrates rich flavors from chicken and melted cheese complemented by the pizza base.

Updated on Fri, 19 Dec 2025 14:21:00 GMT
Melted cheese and juicy chicken filling a golden-brown Leftover Pizza Grilled Cheese. Save
Melted cheese and juicy chicken filling a golden-brown Leftover Pizza Grilled Cheese. | pumpkinvale.com

My roommate called it lazy genius the first time I made this, standing in our tiny kitchen at 11 PM with half a pepperoni pizza staring back at me from the fridge. I had leftover rotisserie chicken and a sudden craving that wouldn't quit, so I did what felt inevitable: folded that cold pizza slice around the chicken, slid it into a hot buttered skillet, and watched it transform into something way better than the sum of its parts. It became our midnight snack weapon, the thing we'd both crave when we had odds and ends taking up real estate in the fridge.

There was this one Sunday afternoon when my mom visited and I casually assembled one of these for her while we talked. She took one bite, raised her eyebrows in that slow-motion way she does when she's genuinely surprised, and asked if I'd learned this from a cookbook. The fact that it came from pure refrigerator desperation felt like my secret, but watching her enjoy it made it feel less like a hack and more like an actual thing I'd created.

Ingredients

  • 2 large slices leftover pizza (any style, preferably with a sturdy crust): Use whatever you have—pepperoni, veggie, BBQ chicken all work beautifully, and the sturdier the crust, the better it holds together when folded.
  • 1 cup cooked shredded chicken (rotisserie or leftover): Rotisserie chicken is the easiest route, but any cooked chicken you've got will do the job and add that much-needed protein.
  • ½ cup shredded mozzarella or cheddar cheese (optional, for extra meltiness): This is where you get to be greedy—extra cheese melts into the crevices and makes the whole thing richer.
  • 2 tbsp unsalted butter, softened: Softened butter spreads evenly and toasts the outside to that perfect golden brown without burning.

Instructions

Set up your canvas:
Place a cold pizza slice on your cutting board with the cheese side facing up. Cold pizza is actually easier to work with because it's less floppy.
Build your filling:
Spread about ½ cup of shredded chicken evenly across the cheese side of each pizza slice. If you want extra richness, sprinkle some additional shredded cheese over the chicken—it'll get all gooey and amazing.
Fold with intention:
Gently fold each pizza slice in half, pressing down lightly so the filling stays tucked inside. Don't press hard or you'll squeeze the filling right out.
Butter your exterior:
Heat your skillet over medium heat while you spread about 1 tbsp of softened butter on the outside of each folded pizza. This is what gets you that golden, crispy exterior.
First sear:
Place the folded pizzas into the hot skillet with the buttered side down. You'll hear a satisfying sizzle. Let them cook undisturbed for 3–4 minutes until the crust turns golden brown and crispy.
The flip:
Using a spatula, gently flip each folded pizza and cook the other side for another 3–4 minutes. The cheese will start melting out the sides a little, which is exactly what you want.
Rest and serve:
Transfer to a plate and let cool for just 1 minute so you don't burn your mouth. Slice in half if you're feeling civilized, and serve hot with whatever dipping sauce calls to you.
Golden, crispy crust perfectly encases the cheesy, chicken-stuffed Leftover Pizza Grilled Cheese. Save
Golden, crispy crust perfectly encases the cheesy, chicken-stuffed Leftover Pizza Grilled Cheese. | pumpkinvale.com

I remember my partner taking a bite and getting that quiet, focused look people get when food genuinely surprises them in the best way. It wasn't fancy or complicated, but it felt like we'd discovered something together, and that made it taste even better than it had any right to.

Pizza Pairings That Actually Work

The beauty of this recipe is that it's almost impossible to mess up because pizza already has a complete flavor profile. Pepperoni and classic cheese are the reliable route, but don't sleep on BBQ chicken pizza folded with shredded chicken—the flavor overlap sounds redundant until you actually taste how well it works. Veggie pizza transforms into something completely different when paired with chicken and extra melted cheese, giving you that surprising contrast between the crispy crust and soft filling.

Dipping Sauce Strategy

This is where the meal gets personality. Marinara feels obvious because pizza, but warm marinara dipped into the crispy folds is legitimately addictive. Ranch brings a cool, creamy contrast that rounds out the richness. Hot sauce works if you want to punch up the flavor and don't mind the heat mixing with melted cheese.

Timing and Temperature Notes

The whole experience happens fast, which is part of why this works as a weeknight solution. Medium heat takes longer than you might expect, but it keeps the crust from charring while the inside actually gets warm. The 3–4 minute windows are real—keep an eye on the color and flip when you see that golden brown start happening.

  • Check your skillet temperature by flicking a tiny water droplet onto it; it should sizzle immediately without disappearing in panic.
  • If your pizza slices are really thick, you might need an extra minute on each side, so adjust based on what you're working with.
  • Let it cool for a full minute or your first bite will hurt, and that's not the kind of memory worth making.
Savory Leftover Pizza Grilled Cheese with melted cheese oozing out, ideal for lunchtime. Save
Savory Leftover Pizza Grilled Cheese with melted cheese oozing out, ideal for lunchtime. | pumpkinvale.com

This recipe proved to me that the best meals often come from happy accidents and leftover curiosity. It's comfort food wearing a clever disguise, the kind of thing that makes you feel resourceful and fed at the same time.

Recipe FAQs

What type of pizza works best for this dish?

Any style with a sturdy crust is ideal, such as pepperoni, veggie, or BBQ chicken pizza, to hold the filling well when folded and toasted.

Can I use other types of cheese?

Mozzarella or cheddar are great for extra meltiness, but feel free to use your preferred melting cheese to enhance flavor and texture.

How should I cook the folded pizza for best results?

Use a nonstick skillet over medium heat with butter on the outside of each folded slice, toasting each side until golden and crispy with melted cheese inside.

Can I add extra flavors inside the fold?

Yes, try adding hot sauce, fresh herbs, or extra shredded cheese inside for added zing and depth of flavor.

Is this suitable as a quick meal or snack?

Absolutely. It takes about 13 minutes total to prepare and cook, making it a perfect speedy option for leftovers.

Leftover Pizza Grilled Cheese

Cold pizza slices folded with shredded chicken and cheese, toasted to crispy, melty perfection in minutes.

Prep Time
5 minutes
Cook Time
8 minutes
Time Needed
13 minutes
Created by Emma Wallace

Recipe Type Easy Everyday Warmth

Skill Level Easy

Cuisine Type American

Makes 2 Serving Size

Diet Information None specified

Ingredient List

Main

01 2 large slices leftover pizza, any style with sturdy crust
02 1 cup cooked shredded chicken, rotisserie or leftover
03 ½ cup shredded mozzarella or cheddar cheese, optional for extra meltiness

For Toasting

01 2 tablespoons unsalted butter, softened

How to Make

Step 01

Arrange Pizza Slice: Place a cold pizza slice on a cutting board, cheese side facing up.

Step 02

Add Chicken and Cheese: Evenly spread ½ cup shredded chicken over the cheese side of each pizza slice and sprinkle additional shredded cheese if desired.

Step 03

Fold Pizza: Fold each pizza slice in half, pressing gently to enclose the filling completely.

Step 04

Prepare Skillet: Heat a large nonstick skillet over medium heat and spread 1 tablespoon butter on the outside of each folded pizza.

Step 05

Toast First Side: Place folded pizzas buttered side down on the skillet and cook for 3 to 4 minutes until golden brown and crisp.

Step 06

Toast Second Side: Flip pizzas carefully with a spatula, press gently, and cook the other side for another 3 to 4 minutes until cheese is melted and crust is golden.

Step 07

Serve: Remove from skillet, allow to cool for 1 minute, slice in half, and serve immediately while hot.

Equipment Needed

  • Large nonstick skillet
  • Spatula
  • Knife and cutting board

Allergy Details

Review ingredients for allergens and ask a healthcare expert if unsure.
  • Contains wheat from pizza crust
  • Contains milk from cheese and butter
  • Possible traces of egg depending on pizza crust or toppings
  • Contains chicken meat
  • Check for additional allergens such as soy or nuts depending on ingredients

Nutritional Breakdown (per serving)

Details shown are for general guidance and aren't a medical substitute.
  • Caloric Content: 480
  • Fats: 23 g
  • Carbohydrates: 38 g
  • Proteins: 32 g